Rituxirel 500mg Injection

Rituxirel 500mg Injection contains Rituximab, a monoclonal antibody used to treat various cancers like Non-Hodgkin's lymphoma and chronic lymphocytic leukemia, as well as autoimmune diseases such as rheumatoid arthritis and pemphigus vulgaris.

Benefits

Rituxirel 500mg Injection selectively targets CD20-positive B-cells, helping to control abnormal B-cell proliferation in cancers and reduce autoimmune-driven inflammation. It is indicated for lymphomas, leukemias, and autoimmune diseases, improving progression-free survival and overall outcomes in various B-cell malignancies.

Uses and Indications

• Non-Hodgkin's Lymphoma.
• Chronic Lymphocytic Leukemia.
• Moderate to severe Rheumatoid Arthritis (in combination with methotrexate).
• Granulomatosis with Polyangiitis.
• Microscopic Polyangiitis.
• Moderate to severe Pemphigus Vulgaris.

The Rituxirel 500mg Injection contains:

• Rituximab IP 500mg (active ingredient).

Dosage and Administration

Rituxirel 500mg Injection is administered as an intravenous infusion by a qualified healthcare professional in a hospital or clinic setting. The exact dosage and treatment schedule are determined by the prescribing physician, based on the specific indication, patient's body surface area, and clinical condition. It should not be self-administered.

Storage and Disposal

• Store in a refrigerator between 2°C and 8°C.
• Keep the container in its outer carton to protect it from light.
• Do not freeze or shake the vial.
• Keep out of the reach of children.
• Diluted solutions should be used immediately or stored refrigerated (2°C to 8°C) for a limited time as per manufacturer guidelines, and any unused portion discarded.

Precautions and Safety

• Rituxirel 500mg Injection is not recommended during pregnancy or while breastfeeding.
• Both men and women must use effective contraception during treatment and for at least 12 months after the last dose.
• Inform your doctor about any pre-existing heart conditions, liver issues, breathing problems, or a history of hepatitis B infection.
• This medicine may lower red and white blood cell counts, increasing the risk of infections. Regular blood tests are necessary to monitor blood cell levels and hepatitis B.
• Avoid live virus vaccines before or during treatment.
• Severe infusion-related reactions can occur during or within 24 hours of administration, requiring immediate medical attention.
• Not recommended for patients with active, severe infections or a weak immune system.

Side Effects and Risks

• Common side effects include headache, weakness, swelling (edema), infections (bacterial, viral), hair loss, nausea, rash, pruritis, fever, chills, low blood pressure, abdominal pain, muscle aches, cough, dizziness, itchy skin, diarrhea, increased sweating, sore throat, muscle spasm, and urinary tract infection.
• Serious infusion-related reactions may include chest pain, difficulty breathing, vomiting, skin rashes, or throat swelling.
• This medication can cause a decrease in white blood cells and platelets.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.