Rituxirel 100mg Injection

Rituxirel 100mg Injection contains Rituximab, a monoclonal antibody used to treat certain types of cancers and autoimmune diseases.

Benefits

Rituxirel 100mg Injection directly targets CD20-positive B-cells, which is crucial for treating lymphomas and leukemias. It helps control autoimmune inflammation in conditions like rheumatoid arthritis and vasculitis, and has been shown to enhance survival rates and prolong remission in B-cell malignancies. The medicine works by reducing the immune response, thereby alleviating pain and inflammation, and by killing or inhibiting the growth and multiplication of cancer cells.

Uses and Indications

• Non-Hodgkin lymphoma (NHL).
• Chronic lymphocytic leukemia (CLL).
• Moderate-to-severe rheumatoid arthritis (in combination with methotrexate).
• Granulomatosis with polyangiitis (GPA).
• Microscopic polyangiitis (MPA).
• Pemphigus vulgaris (PV).

The Rituxirel 100mg Injection contains:

• Rituximab 100mg (active ingredient).

Dosage and Administration

1. Rituxirel 100mg Injection is administered as a slow intravenous infusion under close hospital supervision by a qualified doctor or nurse.
2. The specific dose and frequency of administration will be determined by the prescribing doctor, based on the patient's condition and treatment plan.
3. Pre-treatment screening for infections, such as hepatitis B, is typically required before initiating therapy.
4. Premedication with an antihistamine and acetaminophen is recommended before each infusion to help reduce the incidence and severity of infusion reactions.
5. Do not attempt to self-administer this injection.

Storage and Disposal

• Store Rituxirel 100mg Injection in a refrigerator between 2°C to 8°C.
• Protect the vial from direct sunlight and moisture by storing it in its original carton.
• Do not freeze or shake the vial.
• Keep this medicine out of the reach of children.

Precautions and Safety

• Severe infusion reactions may occur during or within 24 hours after administration. Patients should be closely monitored for symptoms such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling.
• This medicine can lower blood cell counts, which may increase the risk of infection.
• Rituxirel may cause serious liver disease in individuals with current or past hepatitis B infection; screening for hepatitis B is required before starting treatment.
• Rituxirel 100mg Injection is not recommended during pregnancy or while breastfeeding. Effective contraception is important for both males and females during treatment and for a period thereafter.
• Avoid live vaccines during treatment with Rituxirel.
• Inform your doctor if you have heart disease, liver issues, or if you are planning surgery or vaccination.

Side Effects and Risks

• Common side effects include headache, weakness, chills, fever, reactions at the infusion site, lowered blood cell counts, nausea, vomiting, or diarrhea.
• Serious side effects can include difficulty breathing, chest pain, yellowing of the skin or eyes, severe infection, sudden severe rash, unusual bleeding, severe skin reactions (such as Stevens-Johnson syndrome), or a rare brain infection (Progressive Multifocal Leukoencephalopathy - PML).
• Contact your doctor immediately if any serious side effects occur.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.