Pipzo 4.5gm Injection

Pipzo 4.5gm Injection contains Piperacillin (4000mg) and Tazobactam (500mg), a combination antibiotic used to treat a wide range of severe bacterial infections.

Benefits

This injection helps manage and control moderate to severe bacterial infections, offering broad-spectrum coverage against susceptible gram-positive and gram-negative organisms. Tazobactam, a beta-lactamase inhibitor, enhances the effectiveness of Piperacillin by preventing bacterial enzymes from breaking it down. It supports a rapid reduction of infection-related symptoms like fever, pain, and inflammation, helping to prevent the spread of infection and reduce the risk of complications.

Uses and Indications

• Hospital-acquired pneumonia and ventilator-associated pneumonia.
• Urinary tract infections (UTIs).
• Intra-abdominal infections, including complicated appendicitis and peritonitis.
• Skin and soft tissue infections, such as cellulitis, cutaneous abscesses, and ischemic/diabetic foot infections.
• Gynecological infections, including postpartum endometritis and pelvic inflammatory disease.
• Bloodstream infections.

The Pipzo 4.5gm Injection contains:

• Piperacillin 4000mg (as Piperacillin Sodium USP).
• Tazobactam 500mg (as Tazobactam Sodium USP).

Dosage and Administration

1. Pipzo 4.5gm Injection is administered intravenously (IV) by a healthcare professional. It should not be self-administered.
2. The precise dose and schedule are determined by the doctor based on the severity of the illness and patient condition.
3. Administer by infusion over a period of at least 30 minutes.
4. The usual duration of treatment ranges from 5 to 14 days, guided by clinical progress.

Storage and Disposal

• Store below 25°C to 30°C in a cool and dry place, protected from light and moisture.
• Keep out of reach of children and pets.
• After reconstitution, store in a refrigerator at 2-8°C and use within 24 hours.
• Discard any unused solution.

Precautions and Safety

• Inform your doctor about all medicines, supplements, or herbal products you are taking.
• Tell your doctor if you are allergic to any antibiotics (especially penicillins, cephalosporins, or beta-lactamase inhibitors) or have kidney or liver problems.
• Use with caution in patients with renal impairment; dose adjustments may be needed.
• This medicine is generally considered safe during pregnancy and breastfeeding if used under a doctor's supervision.
• Prolonged use may cause diarrhea due to gut bacteria imbalance.
• May reduce potassium levels; patients with electrolyte imbalance should be monitored.
• May increase the risk of seizures; inform your doctor if you have a history of seizures.
• Antibacterial drugs should only be used to treat bacterial infections, not viral infections.
• Complete the full course of therapy to prevent antibiotic resistance.

Side Effects and Risks

• Common side effects include nausea, vomiting, diarrhea, headache, rash, and pain or swelling at the injection site.
• Serious side effects can include severe allergic reactions (swelling, difficulty breathing), kidney damage, abnormal liver function, persistent diarrhea, unusual bleeding, or severe skin reactions. Contact your doctor immediately if these occur.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.