Acabrunat 100mg Capsule 30's

Acabrunat 100mg Capsule contains Acalabrutinib, a targeted therapy prescribed for adults diagnosed with certain blood cancers.

Benefits

Acabrunat 100mg works by inhibiting Bruton's tyrosine kinase (BTK), a protein crucial for the growth and survival of cancer cells. This action helps to slow down or stop the progression of malignant cells in specific types of lymphomas and leukemias. It can be used as a standalone therapy or in combination with other treatments, offering a targeted approach to cancer management.

Uses and Indications

• Mantle cell lymphoma (MCL) in adult patients who have received at least one prior therapy.
• Chronic lymphocytic leukemia (CLL) in adults.
• Small lymphocytic lymphoma (SLL) in adults.

The Acabrunat 100mg Capsule contains:

• Acalabrutinib 100mg (active ingredient).

Dosage and Administration

1. The usual recommended dose is 100 mg, taken orally approximately every 12 hours.
2. Swallow the capsule whole with water; do not open, break, or chew it.
3. Acabrunat 100mg Capsule may be taken with or without food.
4. If a dose is missed by more than 3 hours, skip the missed dose and take the next dose at its regularly scheduled time. Do not take a double dose to compensate.

Storage and Disposal

• Store at room temperature, below 30°C, away from excess heat, light, and moisture.
• Keep this medication out of the sight and reach of children.

Precautions and Safety

• Regular blood tests are necessary to monitor blood cell counts, as well as kidney, liver, and heart functions during treatment.
• This medicine may increase the risk of bleeding; monitor for any unusual bruising or bleeding.
• There is an increased susceptibility to infections; avoid close contact with individuals who are ill.
• Acalabrutinib may cause changes in heart rhythm; report any symptoms of arrhythmias to your doctor.
• Avoid consuming grapefruit and grapefruit juice while on this medication.
• Use effective contraception during treatment and for at least one week after the last dose for women, and avoid breastfeeding for two weeks after the last dose.
• Inform your doctor about all other medications, including over-the-counter drugs and herbal products, due to potential drug interactions.
• Avoid concomitant use with proton pump inhibitors (PPIs). If antacids are used, take Acabrunat at least 2 hours before or after. If H2-receptor antagonists are used, take Acabrunat 2 hours before.
• Use sun protection as this medication may increase the risk of skin cancer.
• Avoid administration in patients with severe hepatic impairment.

Side Effects and Risks

• Common side effects include headache, fatigue, diarrhea, musculoskeletal pain, anemia, neutropenia, upper respiratory tract infection, and thrombocytopenia.
• Serious side effects can include severe bleeding, serious infections (such as pneumonia or sepsis), high blood pressure, and heart problems (including irregular heartbeat or chest pain), and kidney failure.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.