Neukine 300mcg 1ml PFS Injection

Neukine 300mcg 1ml PFS Injection contains Filgrastim (300mcg), a growth factor that stimulates the bone marrow to produce white blood cells, primarily to prevent infections after chemotherapy.

Benefits

Neukine 300mcg Injection reduces the risk of infections in patients undergoing chemotherapy by stimulating the production and activation of neutrophils, a type of white blood cell essential for fighting infections. It also aids in restoring blood cell levels after bone marrow transplantation.

Uses and Indications

• Prevention of infections after chemotherapy due to decreased white blood cells (neutropenia).
• Support following bone marrow transplantation.
• Treatment of severe chronic neutropenia.
• Peripheral blood stem cell mobilization prior to transplantation.
• Neutropenia in HIV-infected individuals.
• Reducing the duration of fever in patients with acute myeloid leukemia.
• Increasing the chance of survival in people exposed to harmful amounts of radiation.

The Neukine 300mcg 1ml PFS Injection contains:

• Filgrastim IP 300mcg (active ingredient) per 1ml pre-filled syringe.

Dosage and Administration

1. Neukine 300mcg 1ml PFS Injection is administered as a subcutaneous (under-skin) injection or as an intravenous infusion by a qualified healthcare professional.
2. The dosage depends on the patient's body weight, the condition being treated, and the response to therapy; it must be determined by the prescribing doctor.
3. The first dose is typically given at least 24 hours after cytotoxic chemotherapy.
4. For a more comfortable injection, allow the pre-filled syringe to warm to room temperature for 30 minutes before use.
5. Do not shake the pre-filled syringe.
6. Use the syringe only once and do not save leftover medicine.

Storage and Disposal

• Store in a refrigerator at 2-8°C (36-46°F).
• Do not freeze.
• Protect from light.
• Keep out of reach of children and pets.
• Discard the medicine if stored at room temperature for more than 48 hours.

Precautions and Safety

• Inform your doctor if you are pregnant, planning to conceive, or breastfeeding, as this medicine is generally not recommended during these periods unless the potential benefits outweigh the risks.
• The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
• Disclose all medications you are currently using to your healthcare team, as many medicines can interact with Neukine.
• Exercise caution if you have pre-existing liver or kidney issues, sickle cell anemia, osteoporosis, or heart problems.
• Seek immediate medical attention if you experience fever, chills, rash, sore throat, swelling around the face or neck, sudden upper-left tummy or shoulder-tip pain, or difficulty breathing.
• Do not use the injection if the liquid has changed color, appears cloudy, or contains visible particles.

Side Effects and Risks

• Common side effects include bone pain, headache, weakness, rash, nausea, fatigue, and reactions at the injection site such as redness, pain, or swelling. Other common effects may include diarrhea, vomiting, hair loss, and fever.
• Rare but serious adverse events reported include spleen enlargement or rupture (splenomegaly), acute respiratory distress syndrome, sickle cell crises in predisposed individuals, capillary leak syndrome, thrombocytopenia (low platelet count), and severe allergic reactions.
• Consult your doctor if any side effects are severe, persist, or significantly impact your quality of life.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.