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Anti D 300mcg 1ml Injection
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Anti D 300mcg 1ml Injection

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Brand BSV

Anti D 300mcg 1ml Injection is an immunoglobulin therapy containing Human Anti-D Immunoglobulin 300mcg, designed to prevent Rh sensitization. This injection is critical for Rh-negative expectant mothers to receive for the sake of their Rh-positive children, assisting in avoiding complications linked to Rh incompatibility during pregnancy and decreasing the chances of hemolytic disease in infants. It also benefits Rh-negative patients who receive Rh-positive blood transfusions and is indicated for the management of immune thrombocytopenic purpura (ITP).


The medicine is administered as an intramuscular injection by healthcare providers only. It is a clear, colorless, and sterile liquid solution, typically supplied in a pre-filled syringe or vial, and does not require reconstitution. For optimal preservation, Anti D 300mcg 1ml Injection must be stored in a refrigerator at 2°C to 8°C and should not be frozen.


Key Features : 

Contains Human Anti-D Immunoglobulin 300mcg to prevent Rh sensitization.
Approved for preventing Rh incompatibility in Rh-negative expectant mothers and Rh-negative patients receiving Rh-positive blood transfusions.
Indicated for the management of immune thrombocytopenic purpura (ITP).
Requires cold-chain storage at 2°C to 8°C; must not be frozen.
Administered via intramuscular injection by qualified medical practitioners.
Manufactured by Bharat Serums And Vaccines Ltd.

Each dose of AntiD 300 mcg/ml Injection contains 300 micrograms of Rho (D) immunoglobulin derived from human plasma formulated in a preservative-free solution. Immunoglobulin neutralizes Rh-positive red blood cells, preventing an immune response in Rh-negative individuals.

Antigen CompositionHuman Anti-D Immunoglobulin 300mcg
Approved IndicationsPrevention of Rh sensitization in Rh-negative expectant mothers; prevention of antibodies after Rh-negative individuals receive Rh-positive blood transfusions; management of immune thrombocytopenic purpura (ITP)
Cold-chain Storage Temperature2°C to 8°C (Do not freeze)
Route of AdministrationIntramuscular injection
Regulatory ApprovalIndian drug regulatory authority (Central Drugs Standard Control Organization) approval for recombinant anti-D immunoglobulin studies; Clinical Trials Registry of India (CTRI No. CTRI/2017/03/008101) registered
Reconstitution RequirementsNo reconstitution required (ready-to-use liquid injection)

This is an intramuscular injection (site of administration for this drug is muscle; most administered to deltoid muscle i.e. upper arm).

Step 1: Locate & Clean 2-inch area around the site with alcohol swab or pad.
Step 2: Prepare and plunge-in the drug into syringe from the vial.
Step 3: Insert the needle & plunge-out at a 90° angle to the skin with a quick thrust.
Step 4: Withdraw the needle at the same angle & press a cotton ball over site.

NOTE: Do not self-administer. It is intended to be used by healthcare professionals only.

  • Any allergic reactions or injection site discomfort should be reported immediately.
  • Contraindications include bleeding disorders and immune system conditions.
  • Avoid use if you have had previous severe immunological reactions.
  • Monitoring patients post-administration is advisable to prevent risks.

Why Is anti d injection Needed?

Anti D injection is a crucial immunoglobulin given to Rh-negative individuals to prevent Rh sensitization, especially in pregnancy. It helps avoid hemolytic disease in newborns by preventing the mother’s immune system from attacking Rh-positive fetal red blood cells. Commonly prescribed as Anti D 300 mg injection is a combination bivalent injection  it is widely used in antenatal and postnatal care.

 

Anti D Injection Use in Pregnancy and After Delivery

Anti D injection during pregnancy or a combination bivalent injection is typically administered around the 28th week and within 72 hours after delivery if the baby is Rh-positive. The Anti D 300 mg injection dose after delivery is vital to protect future pregnancies. It may also be recommended in...

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