Gentacure 30ml Injection

Gentacure 30ml Injection contains Gentamicin Sulphate 40mg/ML, an aminoglycoside antibiotic used to treat a wide range of serious bacterial infections.

Benefits

This medication works by stopping the growth and killing susceptible bacteria, making it effective against various Gram-negative and certain Gram-positive organisms. Its broad-spectrum activity is crucial for managing severe and life-threatening infections.

Uses and Indications

• Blood infections (bacteraemia, septicemia).
• Meningitis and other central nervous system infections.
• Urinary tract infections.
• Respiratory tract infections, including pneumonia.
• Intra-abdominal infections, such as peritonitis.
• Skin and soft tissue infections, including infected wounds or burns.
• Bone and joint infections (osteomyelitis, bacterial arthritis).
• Management of neutropenic patients with suspected bacterial infection.
• Severe neonatal infections.

The Gentacure 30ml Injection contains:

• Gentamicin Sulphate IP 40 mg/mL (active ingredient).
• Excipients typically include sodium metabisulfite, edetate disodium, methylparaben, propylparaben, and water for injection.

Dosage and Administration

Gentacure 30ml Injection is administered by a healthcare professional via intramuscular (IM) injection or slow intravenous (IV) infusion.
For intravenous administration, the injection must be diluted in a suitable sterile solution, such as 0.9% sodium chloride or 5% dextrose, and infused over 30 minutes to 2 hours.
The exact dosage and duration of treatment will be determined by your doctor based on your medical condition, weight, and response to therapy.

Storage and Disposal

• Store vials at room temperature, typically below 25°C.
• Protect from light.
• Do not refrigerate or freeze.
• Discard any unused portion of the diluted solution after 24 hours.
• Keep this medicine out of the reach of children.

Precautions and Safety

• Gentamicin can cause serious side effects, including damage to the kidneys (nephrotoxicity) and inner ear (ototoxicity), which may result in permanent hearing loss or balance problems.
• Your doctor will monitor your kidney function, hearing, and blood levels of gentamicin during treatment to minimize these risks.
• Inform your doctor if you have kidney disease, hearing problems, or muscle weakness (e.g., myasthenia gravis).
• Avoid concurrent use with other medications that can harm the kidneys or ears, such as certain diuretics (e.g., furosemide, ethacrynic acid) or other aminoglycoside antibiotics.
• This medicine may cause fetal harm if used during pregnancy.

Side Effects and Risks

• Common side effects may include injection site pain, rash, itching, nausea, vomiting, and loss of appetite.
• Serious side effects to watch for include ringing in the ears (tinnitus), dizziness, vertigo, hearing loss, changes in urination, swelling of the feet or legs, muscle twitching, or convulsions. Seek immediate medical attention if these occur.
• Severe allergic reactions (anaphylaxis) are rare but possible, characterized by hives, difficulty breathing or swallowing, and swelling of the face or throat.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.