Dobumide 50mg Injection 5ml

Dobumide 50mg Injection 5ml contains Dobutamine Hydrochloride, an inotropic agent used to improve heart function in conditions like heart failure and cardiogenic shock.

Benefits

This medicine works quickly to enhance the heart's pumping action, increasing blood flow and oxygen delivery to vital organs. It is crucial in acute situations where heart contractility is severely impaired, helping to restore normal heartbeat and blood pressure.

Uses and Indications

• Short-term treatment of cardiac decompensation due to depressed contractility.
• Management of acute heart failure and low cardiac output states.
• Support in cardiogenic shock and post-cardiac surgical procedures.
• Used as an alternative to exercise during cardiac stress testing.

The Dobumide 50mg Injection 5ml contains:

• Dobutamine Hydrochloride IP 50 mg/mL (active ingredient).
• Excipients: Sodium metabisulfite, hydrochloric acid and/or sodium hydroxide (for pH adjustment), water for injection.

Dosage and Administration

1. Administered by continuous intravenous infusion.
2. Dosage is individualised by the prescribing doctor, typically starting at 0.5 to 1.0 mcg/kg/min and adjusted based on patient response.
3. Must be diluted before administration with suitable intravenous solutions.

Storage and Disposal

• Store below 25°C.
• Protect from light and do not freeze.
• Keep out of reach of children.
• Discard any unused portion.

Precautions and Safety

• Close monitoring of ECG, blood pressure, and heart rate is essential during administration.
• Hypovolemia should be corrected with suitable volume expanders before starting Dobutamine infusion.
• Use with caution in patients with atrial fibrillation (pre-treat with digitalis if rapid ventricular response) or severe aortic stenosis.
• Contains sodium metabisulfite, which may cause allergic-type reactions, including anaphylactic symptoms and asthmatic episodes, in certain susceptible individuals.

Side Effects and Risks

• Common side effects include increased heart rate (tachycardia), high blood pressure (hypertension), and ventricular ectopic activity.
• Other possible effects include nausea, headache, anginal pain, shortness of breath, and injection site reactions.
• Report any severe or persistent side effects to your doctor.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.