Azothrone 50mg Tablet 10's

Azothrone 50mg Tablet contains Azathioprine, an immunosuppressant used to prevent organ rejection in transplant patients and manage severe autoimmune conditions like rheumatoid arthritis.

Benefits

Azothrone 50mg helps control an overactive immune system, reducing inflammation and preventing the body from attacking its own tissues or rejecting a transplanted organ. It supports long-term disease management and can improve overall quality of life.

Uses and Indications

• Prevention of organ transplant rejection, particularly kidney transplants.
• Management of active rheumatoid arthritis, especially when other treatments have not been effective.
• Treatment of inflammatory bowel disease, including Crohn's disease and ulcerative colitis.
• Management of other autoimmune diseases such as systemic lupus erythematosus, dermatomyositis, polymyositis, autoimmune hepatitis, polyarteritis nodosa, warm autoimmune hemolytic anemia, chronic refractory idiopathic thrombocytopenic purpura, and pemphigus vulgaris.

The Azothrone 50mg Tablet contains:

• Azathioprine 50mg (active ingredient).
• Excipients: Microcrystalline cellulose, Mannitol, Maize starch, Povidone K25, Croscarmellose sodium, Sodium stearyl fumarate, Hypromellose, and Macrogol.

Dosage and Administration

1. Take this medicine by mouth as directed by your doctor, usually once or twice daily.
2. It is often recommended to take Azothrone 50mg Tablet with food to help reduce stomach upset.
3. Do not take this medicine with milk or dairy products, as they may reduce its absorption. If you consume milk or dairy, take Azothrone 50mg Tablet at least 1 hour before or 2 hours after.
4. Your doctor will determine the appropriate dose based on your medical condition, weight, and response to treatment. Do not stop taking this medicine without consulting your doctor.

Storage and Disposal

• Store Azothrone 50mg Tablet at room temperature, typically below 25°C.
• Keep the medicine in a dry place, protected from direct heat, light, and moisture.
• Keep it in the original container, tightly sealed, and out of the reach of children.

Precautions and Safety

• Azathioprine may increase the risk of developing certain types of cancer, including skin cancer and lymphoma. Limit exposure to sunlight and UV light, wear protective clothing, and use a high-factor sunscreen.
• This medicine can lower your body's resistance to infection. Avoid contact with sick individuals and practice frequent hand washing. Do not receive live vaccines without your doctor's approval, and avoid close contact with household members who have recently received live virus vaccines.
• Regular blood tests are necessary to monitor for potential bone marrow suppression, which can lead to low white blood cell, red blood cell, and platelet counts.
• Inform your doctor if you have liver or kidney disease, or certain enzyme disorders (TPMT or NUDT15 deficiency), as these conditions may require dose adjustments or alternative therapies.
• Azathioprine can harm an unborn baby. Use effective birth control during treatment. It passes into breast milk and may affect a nursing infant, so breastfeeding is generally not recommended.
• Discuss all other medications, including over-the-counter drugs and herbal products, with your doctor or pharmacist to avoid potential interactions.

Side Effects and Risks

• Common side effects may include increased stomach irritation, abdominal pain, nausea, vomiting, loss of appetite, and temporary changes in hair color or texture, including hair loss.
• More serious side effects can include unusual bruising or bleeding, fatigue, mouth sores or ulcers, fever, chills, skin rash, and decreased resistance to infection.
• Rarely, patients may experience yellowing of the skin or eyes (jaundice), severe skin reactions, or inflammation of the lungs.
• Contact your doctor immediately if you experience severe nausea, vomiting, diarrhea, fever, unexplained weight loss, night sweats, unusual bleeding or bruising, or any signs of infection.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.