Alburel 20% w/v 100ml Injection

Alburel 20% w/v 100ml Injection contains Human Albumin, a natural protein used to restore and maintain circulating blood volume and manage low albumin levels in various medical conditions.

Benefits

Alburel 20% w/v 100ml Injection helps in the rapid restoration of blood volume, which is crucial in situations of significant fluid loss. It supports stable blood pressure and improves oxygen delivery to vital organs, aiding in patient stabilization and recovery.

Uses and Indications

• Restoration and maintenance of circulating blood volume where volume deficiency has been demonstrated.
• Management of hypovolemia (reduced blood volume) and hypoalbuminemia (low albumin levels).
• Short-term fluid replacement after trauma, excessive bleeding, surgery, or kidney dialysis.
• Adjunctive therapy in severe burns (typically after the initial 24 hours).
• Treatment of acute nephrosis and Adult Respiratory Distress Syndrome (ARDS).
• Used during cardiopulmonary bypass procedures and in Hemolytic Disease of the Newborn.

The Alburel 20% w/v 100ml Injection contains:

• Human Albumin I.P. 20% w/v (active ingredient).

Dosage and Administration

1. Alburel 20% w/v 100ml Injection is for intravenous infusion only and must be administered under the supervision of a healthcare professional.
2. It can be administered undiluted or diluted in isotonic solutions such as 0.9% Sodium Chloride or 5% Dextrose in Water. Do not dilute with water for injections, as this may cause haemolysis.
3. The infusion rate and dosage should be adjusted according to the patient's individual requirements, body weight, severity of illness, and ongoing fluid or protein losses. The daily dose should not exceed 2 g per kg body weight.
4. If large volumes are to be administered, the product should be warmed to room or body temperature before use.
5. Do not use solutions that are cloudy or contain deposits. Once the container has been opened, the contents should be used immediately, and any unused portion must be discarded within four hours.

Storage and Disposal

• Store Alburel 20% w/v 100ml Injection between 2°C and 25°C.
• Do not freeze the solution.
• Keep the vial in the outer carton to protect it from light.
• Keep out of the sight and reach of children.

Precautions and Safety

• Alburel 20% w/v 100ml Injection is contraindicated in individuals with a known hypersensitivity to albumin preparations or any component of the formulation.
• Exercise caution in patients with severe anemia, heart failure with normal or increased intravascular volume, high blood pressure, enlarged veins in the gut, pulmonary oedema, a tendency to bleed, or decreased/no urine production.
• Patients should be closely monitored for circulatory status, electrolyte balance, blood volume, and blood pressure during administration to prevent fluid overload.
• Consult a doctor before use if pregnant or breastfeeding.
• Do not mix with protein hydrolysates, amino acid solutions, or solutions containing alcohol.

Side Effects and Risks

• Common side effects may include flushing (a sense of warmth or redness), nausea, vomiting, chills, and fever. These usually resolve as the body adjusts to the medicine.
• Rarely, allergic reactions such as urticaria, skin rash, changes in respiration, pulse, or blood pressure may occur. Seek immediate medical attention if these symptoms worsen.
• There is a risk of fluid overload, especially with rapid infusion or in patients with compromised cardiac or renal function.

Disclaimer

Use this medicine only under the prescription and guidance of a qualified doctor or pharmacist.